Lucile Astorgues-Xerri Selected Research

compound 0118

9/2014	OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis.
6/2012	Antitumor agent calixarene 0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding.

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Lucile Astorgues-Xerri Research Topics

Disease

15	Neoplasms (Cancer) 12/2022 - 05/2009
2	Colonic Neoplasms (Colon Cancer) 05/2010 - 05/2009
1	Adenocarcinoma 12/2022
1	Carcinogenesis 03/2021
1	Leukemia 12/2019
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Triple Negative Breast Neoplasms 01/2017
1	Malignant Mesothelioma 01/2017
1	Mesothelioma 01/2017
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 12/2016
1	Glioblastoma (Glioblastoma Multiforme) 11/2016
1	Neuroblastoma 01/2016
1	Carcinoma (Carcinomatosis) 01/2015
1	Neoplasm Metastasis (Metastasis) 03/2014
1	Necrosis 05/2010

Drug/Important Bio-Agent (IBA)

6	OTX015IBA 12/2019 - 01/2016
3	Galectin 1 (LGALS1)IBA 09/2014 - 06/2012
2	compound 0118IBA 09/2014 - 06/2012
2	calix(4)areneIBA 10/2013 - 06/2012
2	Protein Kinase CIBA 05/2010 - 05/2009
1	PeriostinIBA 12/2022
1	Progesterone FDA LinkGeneric 01/2017
1	Everolimus FDA Link 01/2017
1	Estrogens (Estrogen)FDA Link 01/2017
1	Gemcitabine FDA Link 01/2017
1	Cisplatin (Platino)FDA LinkGeneric 01/2017
1	Pemetrexed (MTA)FDA Link 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2016
1	DNA (Deoxyribonucleic Acid)IBA 01/2016
1	ChromatinIBA 01/2016
1	Peptide Hydrolases (Proteases)FDA Link 01/2015
1	Monoclonal AntibodiesIBA 01/2015
1	cathepsin SIBA 01/2015
1	Antineoplastic Agents (Antineoplastics)IBA 09/2014
1	saccharide-binding proteinsIBA 09/2014
1	Peptides (Polypeptides)IBA 10/2013
1	Calixarenes (Calixarene)IBA 10/2013
1	Cytotoxins (Cytolysins)IBA 10/2013
1	Angiogenesis InhibitorsIBA 06/2012
1	Cadherins (E-Cadherin)IBA 05/2010
1	Transforming Growth Factor beta (TGF-beta)IBA 05/2010
1	VimentinIBA 05/2010
1	enzastaurinIBA 05/2010
1	Messenger RNA (mRNA)IBA 05/2010
1	Protein Kinases (Protein Kinase)IBA 05/2010
1	Protein Kinase C betaIBA 05/2010
1	StaurosporineIBA 05/2009
1	3-ingenyl angelateIBA 05/2009

Therapy/Procedure

6	Therapeutics 01/2019 - 10/2013
2	Drug Therapy (Chemotherapy) 03/2021 - 11/2016